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We do not supply
chromium electrodes because it is a known carcinogen.
GENERAL
PROPERTIES
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Symbol:
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Cr
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Atomic
Number:
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24
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Atomic
Weight:
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51.996
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Density:
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7.18
gm/cc
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Melting
Point:
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1857
oC
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Boiling
Point:
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2672
oC
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Thermal
Conductivity:
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0.939
W/cm/oK
@ 298.2 oK
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Electrical
Resistivity:
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12.9
microhm-cm @ 0 oC
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Electronegativity:
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1.6
Paulings
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Specific
Heat:
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0.107
Cal/g/oK
@ 25 oC
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Heat
of Vaporization:
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72.97
K-cal/gm atom at 2672 oC
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Heat
of Fusion:
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3.66
Cal/gm mole
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MATERIAL
OVERVIEW
Characteristics:
Hard brittle semi-gray metal. Compounds have strong and varied colors. Cr
ion forms many coordination compounds. Exists in active and passive forms
the latter giving rise to its corrosion resistance due to a thin surface
oxide layer that passivates the metal when treated with oxidizing agents.
Active form reacts readily with dilute acids to form chromous salts.
Soluble in acids (except nitric) and strong alkalies; insoluble in water.
Derivation:
From chromite (q.v.) by direct reduction (ferrochrome); by reducing the
oxide with finely divided aluminum or carbon; and by electrolysis of
chromium solutions.
Hazard:
Hexavalent chromium compounds have an irritating and corrosive effect on
tissue resulting in ulcers and dermatitis on prolonged contact. Tolerance
for chromium dust and fume is 0.5 mg/m3
of
air. It is a known carcinogen (OSHA).
Chromium Q & A
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I read where chromium picolinate is recommended for people with hypoglycemia.
Can a person vary on the amount taken daily? (i.e. take more when in
a bad mood)
Also, is there a certain amount of sugar
able to be taken that won't effect one's emotional
state? Also, is there a recommended diet? Thank you in advance.
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First of all, sweets do affect a person's mood, but with varying
results from different amounts. Secondly, chromium as a mineral
functions as a glucose tolerance factor, but the question is, what
amount is appropriate as a supplement and can it be toxic?
It is not recommended to use chromium picolinate to control blood
sugar levels. There is no proof that chromium supplements can help
treat or prevent diabetes
and other health problems. Methods to assess chromium amounts in the
body are lacking, but chromium is stored in hair
and blood (serum). However, hair analysis is not a valid method to
analyze nutritional status of chromium or any other nutrient.
It is relatively easy to get safe and adequate amounts of
chromium (50-200 micrograms per day) by eating a variety of foods
like brewer's yeast, calf's liver, American cheese and wheat germ.
People who take chromium picolinate supplements may suffer health
problems rather than improved health. Although claims of weight
loss, lowered cholesterol
and reversal of diabetes
are unfounded, researchers have shown that chromium supplements
damaged cell chromosomes which are the blueprints for a cell's
function and reproduction. It is generally thought that cancer
starts with a change to the genetic material in a cell causing it to
grow and reproduce without restraint.
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How effective and safe are Chromium Picolinate and Fenfluramine
as appetite suppressants?
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Chromium Picolinate is sold over the counter as a nutritional supplement.
Chromium works with insulin
in assisting cells to take in glucose and release energy. Chromium
Picolinate has not been shown to cause weight
loss and its ability to improve insulin effectiveness is being
questioned.
Fenfluramine is the chemical name of a drug
that inhibits the release of serotonin in the brain. Serotonin is
the "feel good me" drug that the brain produces.
Tryptophan (an amino
acid found in complete proteins, especially turkey and chicken)
is a precursor of serotonin. In addition, carbohydrates increase the
serotonin levels in the brain. Exercise
increases these neurotransmitters in the brain. Fenfluramine is
being looked at as an anti-obesity drug. Research so far indicates
that when the drug is stopped, weight can be regained. Ask you
doctor about Fenfluramine.
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What do you know about Chromium Picolinate?
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Chromium Picolinate is sold over the counter as a nutritional supplement.
Chromium works with insulin
in assisting cells to take in glucose and release energy. When
Chromium is lacking, the effectiveness of insulin is lessened and
impaired tolerance to glucose. Deficiency is rare except in persons
who must rely completely on intravenous fluids (hyperalimentation)
for long term.
There had been scientific references that suggested that
supplementing with Chromium Picolinate would enhance insulin
utilization. That has not proven consistently true in current
research.
Chromium can be measured in hair and blood. But laboratory
methods to determine chromium levels are lacking. This is why a
chromium requirement has not been determined. There is no Recommended
Dietary Allowances (RDA) for Chromium. Toxicity of chromium is
low according to the National Academy of Sciences. However since
people have started to supplement with chromium picolinate, there
have been several cases of toxicity which resulted in chronic renal
failure and accumulation of chromium in tissues. Persons with behavior
disorders are warned to avoid chromium supplements.
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I've seen Chromium Picolinate advertised recently as a
"metabolism boosting" diet supplement. Is there any merit
to this claim?
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Quite frankly, no. Initially there was some speculation that
since Chromium is a component of the hormone insulin
that additional Chromium would enhance insulin's ability to break
down glucose. Research has not supported this concept.
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Is there any relationship between strenuous exercise,
chromium and insulin
resistance?
Would you consider a chromium supplement with reduction in sugar
consumption?
What are natural sources of chromium?
Does magnesium also factor into this?
I exercise treadmill/Stairmaster 6/7 days a week and blood sugar
recently was up to 160 - 190 ranges. Lower
carbohydrate/ sugar has reduced this level. Thanks.
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Exercise
probably decreases insulin resistance if the exercise reduces body
fat which is one cause of increased insulin resistance. Your
exercise program sounds good, but you should talk to an exercise
physiologist about adding some weight training exercises.
Chromium is involved in the production of insulin
and the release of glucose's energy from cells. Taking a chromium
supplement will not increase the production of insulin unless your
diet is deficient in chromium. Your body releases insulin from your
pancreas in response to an elevated blood sugar level. Recent
research does not support taking a chromium supplement for persons
with diabetes
or pre-diabetic insulin resistance.
Food sources of chromium are meats, unrefined foods (whole
grains, fruits and vegetables), fats and vegetable oils.
Sugar reduction
is always an improvement to a healthy diet and reducing an elevated
blood glucose. You may want to talk to a Registered
Dietitian about a diabetic meal plan as a blood sugar of 160 to
180 is more than a slight elevation. Fasting blood glucose should be
70 to 110 mg/dl. It is normal for blood glucose to double within 2
hours after a meal. When was your blood glucose taken? After a meal
or fasting in the morning?
Magnesium is involved with calcium
and phosphorus in depositing these minerals in bones and teeth, the
transmission of nerve impulses, building of protein structures,
enzymes and muscle contraction. Based on today's knowledge,
magnesium is not involved in blood glucose levels or insulin
production.
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Chromium
The evidence for chromium (Cr) as an essential trace
mineral in animals was obtained in rats fed a Torula yeast-based
diet. They developed abnormal glucose tolerance that could be reversed by
supplements of brewer's yeast, thought to contain a glucose tolerance
factor. Trivalent chromium (CrCl3) was later reported to be the
active factor in brewer's yeast. Further, it was reported that chromium
formed a complex with insulin that enhanced insulin's activity. However,
the relevance of animal studies of chromium deficiency to the effects of
chromium in humans remains controversial. Glucose tolerance factor has
never been isolated nor its structure determined. The insulin receptor has
been purified and characterized without finding any evidence of chromium
as a component of its subunits, as an accessory chromoprotein for insulin
binding, or as a second messenger in mediating the effect of insulin on
cells. Unlike iron, zinc, copper, molybdenum, and selenium, chromium has
not been found in a metalloprotein with biologic activity. Therefore, the
apparent biologic activity of chromium in promoting glucose tolerance
remains unexplained.
The estimated requirement for chromium in humans is about
1 µg/day, but only 1 to 3% of trivalent chromium is absorbed. In the USA,
chromium intakes range from 20 to 50 µg/day, with plasma levels from 0.05
to 0.50 µg/L (1.0 to 9.6 nmol/L). The Food and Nutrition Board of the
NAS/NRC states that a safe, adequate intake of chromium for an adult is 50
to 200 µg/day.
Deficiency:
Apparent chromium deficiency
that was associated with glucose intolerance and peripheral neuropathy
occurred in four patients receiving long-term TPN. Three responded to
doses of 150 to 250 µg of trivalent chromium, with a reduction in
peripheral neuropathy and an increase in glucose tolerance.
Toxicity:
Trivalent chromium may cause
skin irritation at high doses given parenterally but is not toxic at the
lower doses given orally. Persons may be exposed to hexavalent chromium
(CrO3) in the workplace. It is irritable to the skin, lungs,
and GI tract and can cause perforation of the nasal septum and carcinoma
of the lung.
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