TELOMERES
and Possible
Regeneration
using
PRESCHIS
antioxidant
A major thrust of Biophysica's research since 1992, originally supported by a grant from the National Research Council of Canada, is in possible regeneration of Pineal, Pituitary and Telomeres using electromagnetic energy, signals and frequencies emitted by the Pinealstim generator. We now have Trans-Cerebral and whole body stimulation devices which emit longitudinal Scalar EM waves. This new technology might possibly be promising in protecting and regenerating telomeres and we invite interested research investors.
Telomeres are specialized DNA-protein complex at ends of linear chromosomes. They are essential for proper maintenace of chromosomes, and play a major role in aging and cancer. Telomerases are specialized reverse transcriptases that are involved in synthesis of telomeres in most organisms. They are very interesting DNA polymerases in that they carry RNA template within them.
T he excitement over telomerase continues to mount as evidence accumulates that makes the connection between telomere length and cell lifespan likely to be more than a coincidence. The most recent findings show that the age span of cultured cells, normally limited to around 50 to 90 cell doublings--the so-called Hayflick limit, named for the scientist who first observed that the lifespan of cultured cells was finite--can be more than doubled by transfecting them with telomerase genes (A.G. Bodnar et al., Science, 279:349-52, 1998). These findings come on the heels of a series of observations correlating the loss of telomerase activity and/or the shortening of the ends of chromosomes (telomeres) with the loss of proliferative capacity, an observation that holds true in a number of situations: somatic (limited proliferative capacity) as compared to germ cells (larger proliferative capacity); normal tissue (limited) versus malignant tumors (unlimited); and normal T cells versus HIV-infected T cells, whose telomeres resemble those of aged individuals.